California remains at the forefront of technological advancement, and in no field is this more apparent than healthcare. The intersection of AI, digital therapeutics, and operational automation is giving rise to a new generation of HealthTech startups with the potential to transform how care is delivered, accessed, and financed. Below is a curated ranking of the top 10 HealthTech startups based in California, listed from number 10 to number 1. Each of these ventures represents a powerful shift in healthcare, offering scalable solutions to address some of the most persistent inefficiencies in the industry.
#10: Meru Health (San Mateo, CA)
Meru Health is redefining mental health care by offering an evidence-based digital clinic designed to treat depression, anxiety, and burnout. The company integrates licensed therapists, anonymous peer support, and biofeedback to deliver outcomes that are measurable and sustained. Meru Health’s platform is increasingly adopted by employers and insurers, as demand for scalable mental health solutions accelerates across the U.S.
#9: Omada Health (San Francisco, CA)
Omada Health has positioned itself as a leader in digital chronic care. Its platform leverages behavioral science and digital coaching to manage prediabetes, diabetes, hypertension, and musculoskeletal conditions. By combining connected devices with personalized coaching and rich analytics, Omada is delivering meaningful improvements in long-term health outcomes. The company has rapidly expanded its partnerships with insurers and health systems, earning it a spot as one of California’s most mature and effective HealthTech solutions.
#8: Suki (Redwood City, CA)
Suki offers an AI-powered voice assistant built specifically for healthcare providers. Founded by Punit Soni, a former Google executive, Suki helps clinicians create clinical notes and navigate EHR systems using natural language. By automating administrative tasks, Suki significantly reduces clinician burnout and improves accuracy and efficiency. Integrated with major EHR platforms, it is already in use across hundreds of hospitals and clinics.
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#7: Ellipsis Health (San Francisco, CA)
Ellipsis Health uses AI to detect and monitor mental health conditions through voice analysis. Its ambient AI agent, Sage, speaks with patients post-visit and tracks emotional health over time. Trained on over two million clinical interactions, the system is being deployed by payers and providers to close care gaps, increase patient engagement, and improve medication adherence. Backed by CVS Health Ventures, Khosla Ventures, and Salesforce, Ellipsis is expanding rapidly.
#6: Tebra (Newport Beach, CA)
Formed through the merger of Kareo and PatientPop, Tebra provides a comprehensive platform that enables independent practices to thrive. It integrates EHR, practice management, billing, marketing, and analytics in one system. Designed for private practices, Tebra allows providers to streamline their operations and compete effectively in a challenging healthcare landscape. Its scale and versatility make it a standout infrastructure play in the HealthTech space.
#5: Abridge (San Francisco, CA)
Abridge is an ambient AI platform that captures and transcribes doctor-patient conversations, automatically generating clinical notes and structured documentation. With a growing footprint in over 150 health systems and partnerships with major EHR platforms, Abridge is easing the burden of administrative documentation while improving billing accuracy. In 2025, it raised $300 million in a Series E round led by Andreessen Horowitz and Khosla Ventures, doubling its valuation to $5.3 billion.
#4: Hippocratic AI (Palo Alto, CA)
Hippocratic AI focuses on developing large language models (LLMs) optimized for non-diagnostic healthcare applications, such as follow-up calls, patient education, and care coordination. What sets the company apart is its safety-first approach, emphasizing low latency, high accuracy, and empathetic interactions. With early partnerships and pilots in health systems and payers, Hippocratic is laying the groundwork for safe and scalable AI agents in healthcare.
#3: Viz.ai (San Francisco, CA)
Viz.ai uses artificial intelligence to synchronize stroke care and other critical diagnoses across clinical teams. The platform leverages real-time imaging and data sharing to ensure fast and accurate treatment decisions, often within minutes. Already FDA-cleared for several applications and adopted by over 1,300 hospitals, Viz.ai has demonstrated the tangible life-saving impact of AI in acute care settings.
#2: Kintsugi (Berkeley, CA)
Kintsugi uses voice biomarkers and machine learning to detect signs of depression and anxiety within short voice samples. The company is pioneering a non-invasive, infrastructure-light approach to mental health diagnostics, offering APIs that integrate easily into existing call centers, telehealth systems, and digital health platforms. Its novel model allows earlier identification and intervention, potentially revolutionizing population-level mental health strategies.
#1: Forward (Los Angeles, CA)
Topping this year’s list, so far, is Forward, a new type of healthcare system that combines advanced medical devices, real-time diagnostics, and AI-backed doctor visits within beautifully designed clinics. Forward’s membership-based model includes continuous health monitoring, predictive analytics, and 24/7 access to care. Its unique blend of hardware, software, and services aims to reinvent the primary care experience from the ground up. With facilities in multiple U.S. cities and plans for international expansion, Forward represents the most comprehensive and forward-looking vision for HealthTech in 2024.
These ten companies are not only building powerful products but actively reshaping the healthcare industry. Each combines technological sophistication with a deep understanding of clinical and operational challenges. From ambient AI assistants to decentralized diagnostics and predictive analytics, these ventures offer a glimpse into the future of care—personalized, efficient, and scalable. California remains their launchpad, but their reach and impact are global.
